Abstract
Leukocytes are rapidly recruited to the preovulatory ovary and play a crucial role as facilitators of ovulation and luteal formation. In this article, recent findings on leukocyte trafficking to the ovary, as well as the physiological role of leukocytes in the ovary, will be summarized and discussed. We then explore the novel hypothesis that the hypothalamus-pituitary-ovary (HPO) axis might include the spleen as a reservoir of leukocytes by summarizing recent reports on this topic, both in the fields of immunology and reproductive biology.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 345-352 |
| Number of pages | 8 |
| Journal | Trends in Endocrinology and Metabolism |
| Volume | 22 |
| Issue number | 9 |
| DOIs | |
| State | Published - Sep 1 2011 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism
- Endocrinology
Cite this
Pituitary-ovary-spleen axis in ovulation. / Oakley, Oliver R.; Frazer, Michele L.; Ko, CheMyong.
In: Trends in Endocrinology and Metabolism, Vol. 22, No. 9, 01.09.2011, p. 345-352.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Pituitary-ovary-spleen axis in ovulation
AU - Oakley, Oliver R.
AU - Frazer, Michele L.
AU - Ko, CheMyong
PY - 2011/9/1
Y1 - 2011/9/1
N2 - Leukocytes are rapidly recruited to the preovulatory ovary and play a crucial role as facilitators of ovulation and luteal formation. In this article, recent findings on leukocyte trafficking to the ovary, as well as the physiological role of leukocytes in the ovary, will be summarized and discussed. We then explore the novel hypothesis that the hypothalamus-pituitary-ovary (HPO) axis might include the spleen as a reservoir of leukocytes by summarizing recent reports on this topic, both in the fields of immunology and reproductive biology.
AB - Leukocytes are rapidly recruited to the preovulatory ovary and play a crucial role as facilitators of ovulation and luteal formation. In this article, recent findings on leukocyte trafficking to the ovary, as well as the physiological role of leukocytes in the ovary, will be summarized and discussed. We then explore the novel hypothesis that the hypothalamus-pituitary-ovary (HPO) axis might include the spleen as a reservoir of leukocytes by summarizing recent reports on this topic, both in the fields of immunology and reproductive biology.
UR - http://www.scopus.com/inward/record.url?scp=80052370553&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=80052370553&partnerID=8YFLogxK
U2 - 10.1016/j.tem.2011.04.005
DO - 10.1016/j.tem.2011.04.005
M3 - Review article
C2 - 21600783
AN - SCOPUS:80052370553
VL - 22
SP - 345
EP - 352
JO - Trends in Endocrinology and Metabolism
JF - Trends in Endocrinology and Metabolism
SN - 1043-2760
IS - 9
ER -