Pitch-dependent acceleration of neurite outgrowth on nanostructured anodized aluminum oxide substrates

Woo Kyung Cho, Kyungtae Kang, Gyumin Kang, Min Jee Jang, Yoonkey Nam, Insung S. Choi

Research output: Contribution to journalArticlepeer-review

Abstract

Pitching in to help: When nanostructured anodized aluminum oxide substrates of four different types were used as nanotopographical environments for in vitro neuronal culture, the average neurite outgrowth was much faster on surfaces with a 400 nm pitch than on surfaces with a 60 nm pitch (see AFM images of two substrates and fluorescence micrographs of hippocampal neurons after culture for 2 days on these substrates).

Original languageEnglish (US)
Pages (from-to)10114-10118
Number of pages5
JournalAngewandte Chemie - International Edition
Volume49
Issue number52
DOIs
StatePublished - Dec 27 2010
Externally publishedYes

Keywords

  • anodized aluminum oxide
  • cell adhesion
  • nanostructures
  • neurite outgrowth
  • neurochemistry

ASJC Scopus subject areas

  • Catalysis
  • General Chemistry

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