Pigmented epidermal plaques in three dogs

Laura B. Stokking, Eugene J. Ehrhart, Carol A. Lichtensteiger, Karen L. Campbell

Research output: Contribution to journalArticlepeer-review


Papillomavirus was identified in pigmented epidermal plaques (PEP) from three dogs: a miniature schnauzer with hyperadrenocorticism and hypoglobulinemia, an American Staffordshire terrier with hypoglobulinemia, and a Pomeranian with unconfirmed hypothyroidism. Squamous cell carcinoma (SCC) arose within several plaques in the Pomeranian. Clinical improvement coincided in the first two cases with treatment of the concurrent disease and the administration of low-dose oral interferon-α. This is the first report of PEP in an American Staffordshire terrier and a Pomeranian. The potential for malignant transformation of PEP to SCC emphasizes the need for recognition and clinical management of PEP.

Original languageEnglish (US)
Pages (from-to)411-417
Number of pages7
JournalJournal of the American Animal Hospital Association
Issue number5
StatePublished - 2004

ASJC Scopus subject areas

  • Small Animals


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