Physical Activity for Strengthening Fracture Prone Regions of the Proximal Femur

Robyn K. Fuchs, Mariana E. Kersh, Julio Carballido-Gamio, William R. Thompson, Joyce H. Keyak, Stuart J. Warden

Research output: Contribution to journalReview articlepeer-review


Purpose of Review: Physical activity improves proximal femoral bone health; however, it remains unclear whether changes translate into a reduction in fracture risk. To enhance any fracture-protective effects of physical activity, fracture prone regions within the proximal femur need to be targeted. Recent Findings: The proximal femur is designed to withstand forces in the weight-bearing direction, but less so forces associated with falls in a sideways direction. Sideways falls heighten femoral neck fracture risk by loading the relatively weak superolateral region of femoral neck. Recent studies exploring regional adaptation of the femoral neck to physical activity have identified heterogeneous adaptation, with adaptation principally occurring within inferomedial weight-bearing regions and little to no adaptation occurring in the superolateral femoral neck. Summary: There is a need to develop novel physical activities that better target and strengthen the superolateral femoral neck within the proximal femur. Design of these activities may be guided by subject-specific musculoskeletal modeling and finite-element modeling approaches.

Original languageEnglish (US)
Pages (from-to)43-52
Number of pages10
JournalCurrent Osteoporosis Reports
Issue number1
StatePublished - Feb 1 2017


  • Bone density
  • Bone mass
  • Bone structure
  • Exercise
  • Femoral neck
  • Osteoporosis

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism


Dive into the research topics of 'Physical Activity for Strengthening Fracture Prone Regions of the Proximal Femur'. Together they form a unique fingerprint.

Cite this