TY - JOUR
T1 - Physical activity and self-reported cardiovascular comorbidities in persons with multiple sclerosis
T2 - Evidence from a cross-sectional analysis
AU - Motl, Robert W.
AU - Fernhall, Bo
AU - McAuley, Edward
AU - Cutter, Gary
PY - 2011/6
Y1 - 2011/6
N2 - Background: This study examined the possibility of a linear, inverse association between physical activity and the number of self-reported cardiovascular comorbidities in persons with multiple sclerosis (MS). Methods: The sample included 561 persons with MS who completed demographic, cardiovascular comorbidity, disability status, and physical activity self-report assessments, and then wore an accelerometer for 7 days. The data were analyzed using bivariate correlation and multiple linear regression analyses. Results: Bivariate correlation analysis indicated that there were statistically significant, inverse associations between the number of self-reported cardiovascular comorbidities and objectively measured (r = -0.192, p = 0.0001) and self-reported (r = -0.151, p = 0.0001) physical activity. The first multiple linear regression indicated that objectively measured physical activity was significantly associated with the number of self-reported cardiovascular comorbidities (B = -0.003, SE B = 0.001, β = -0.128), even after controlling for confounding variables. The second multiple linear regression indicated that self-reported physical activity, too, was significantly associated with the number of self-reported cardiovascular comorbidities (B = -0.011, SE B = 0.004, β = -0.114), even after controlling for confounding variables. Conclusion: Physical activity was associated with the number of self-reported cardiovascular comorbidities, independent of disability status and other possible confounding variables, in persons with MS.
AB - Background: This study examined the possibility of a linear, inverse association between physical activity and the number of self-reported cardiovascular comorbidities in persons with multiple sclerosis (MS). Methods: The sample included 561 persons with MS who completed demographic, cardiovascular comorbidity, disability status, and physical activity self-report assessments, and then wore an accelerometer for 7 days. The data were analyzed using bivariate correlation and multiple linear regression analyses. Results: Bivariate correlation analysis indicated that there were statistically significant, inverse associations between the number of self-reported cardiovascular comorbidities and objectively measured (r = -0.192, p = 0.0001) and self-reported (r = -0.151, p = 0.0001) physical activity. The first multiple linear regression indicated that objectively measured physical activity was significantly associated with the number of self-reported cardiovascular comorbidities (B = -0.003, SE B = 0.001, β = -0.128), even after controlling for confounding variables. The second multiple linear regression indicated that self-reported physical activity, too, was significantly associated with the number of self-reported cardiovascular comorbidities (B = -0.011, SE B = 0.004, β = -0.114), even after controlling for confounding variables. Conclusion: Physical activity was associated with the number of self-reported cardiovascular comorbidities, independent of disability status and other possible confounding variables, in persons with MS.
KW - Cardiovascular comorbidities
KW - Multiple sclerosis
KW - Physical activity
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U2 - 10.1159/000327749
DO - 10.1159/000327749
M3 - Article
C2 - 21597305
AN - SCOPUS:79955954764
SN - 0251-5350
VL - 36
SP - 183
EP - 191
JO - Neuroepidemiology
JF - Neuroepidemiology
IS - 3
ER -