Physical activity and cognitive function in multiple sclerosis

Robert W. Motl, Eduard Gappmaier, Kathryn Nelson, Ralph H.B. Benedict

Research output: Contribution to journalArticlepeer-review


Cognitive impairment is prevalent, disabling, and poorly managed in persons with multiple sclerosis (MS). This cross-sectional study examined the associations among physical activity, cognitive processing speed, and learning and memory in 33 persons with MS who underwent neuropsychological assessments and wore a physical activity monitor for 7 days. Cognitive impairment was greatest in cognitive processing speed. Physical activity was significantly correlated with cognitive processing speed (pr =.35), but not learning and memory (pr =.20), after controlling for sex, age, and education. Researchers should examine exercise training and physical activity effects on cognitive performance, particularly processing speed, in MS.

Original languageEnglish (US)
Pages (from-to)734-741
Number of pages8
JournalJournal of Sport and Exercise Psychology
Issue number5
StatePublished - Oct 2011


  • Cognitive impairment
  • Exercise
  • Multiple sclerosis

ASJC Scopus subject areas

  • Applied Psychology


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