Photonics-on-a-chip: Recent advances in integrated waveguides as enabling detection elements for real-world, lab-on-a-chip biosensing applications

Adam L. Washburn, Ryan C. Bailey

Research output: Contribution to journalReview articlepeer-review

Abstract

By leveraging advances in semiconductor microfabrication technologies, chip-integrated optical biosensors are poised to make an impact as scalable and multiplexable bioanalytical measurement tools for lab-on-a-chip applications. In particular, waveguide-based optical sensing technology appears to be exceptionally amenable to chip integration and miniaturization, and, as a result, the recent literature is replete with examples of chip-integrated waveguide sensing platforms developed to address a wide range of contemporary analytical challenges. As an overview of the most recent advances within this dynamic field, this review highlights work from the last 2-3 years in the areas of grating-coupled, interferometric, photonic crystal, and microresonator waveguide sensors. With a focus towards device integration, particular emphasis is placed on demonstrations of biosensing using these technologies within microfluidically controlled environments. In addition, examples of multiplexed detection and sensing within complex matrices - important features for real-world applicability - are given special attention.

Original languageEnglish (US)
Pages (from-to)227-236
Number of pages10
JournalAnalyst
Volume136
Issue number2
DOIs
StatePublished - Jan 21 2011

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Environmental Chemistry
  • Spectroscopy
  • Electrochemistry

Fingerprint Dive into the research topics of 'Photonics-on-a-chip: Recent advances in integrated waveguides as enabling detection elements for real-world, lab-on-a-chip biosensing applications'. Together they form a unique fingerprint.

Cite this