TY - GEN
T1 - Photonic metamaterial surfaces for digital resolution biosensor microscopies using enhanced absorption, scattering, and emission
AU - Cunningham, Brian T.
AU - Canady, Taylor D.
AU - Zhao, Bin
AU - Ghosh, Shreya
AU - Li, Nantao
AU - Huang, Qinglan
AU - Xiong, Yanyu
AU - Fried, Glenn
AU - Kohli, Manish
AU - Demirci, Utkan
AU - Wang, Xing
N1 - Publisher Copyright:
© 2021 SPIE. All rights reserved.
PY - 2021
Y1 - 2021
N2 - Newly demonstrated advanced biosensor imaging technologies utilize the unique electromagnetic capabilities of photonic metamaterials to enhance the interaction between light and biological matter. The resulting capabilities address gaps in existing technologies for biomolecular analysis that rely upon enzymatic and chemical amplification, costly instrumentation, and complex assay protocols. Through amplification of the excitation/extraction efficiency of light emitting tags, absorption efficiency of nanoparticle tags, and scattering efficiency of biological analytes, technology platforms have been demonstrated that are capable of ultrasensitive, digital-resolution, room temperature, isothermal, rapid, and highly quantitative biomolecular analysis.
AB - Newly demonstrated advanced biosensor imaging technologies utilize the unique electromagnetic capabilities of photonic metamaterials to enhance the interaction between light and biological matter. The resulting capabilities address gaps in existing technologies for biomolecular analysis that rely upon enzymatic and chemical amplification, costly instrumentation, and complex assay protocols. Through amplification of the excitation/extraction efficiency of light emitting tags, absorption efficiency of nanoparticle tags, and scattering efficiency of biological analytes, technology platforms have been demonstrated that are capable of ultrasensitive, digital-resolution, room temperature, isothermal, rapid, and highly quantitative biomolecular analysis.
KW - Biosensors
KW - Diagnostics
KW - Enhanced fluorescence
KW - Photonic crystals
KW - Photonic metamaterials
UR - http://www.scopus.com/inward/record.url?scp=85108458318&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85108458318&partnerID=8YFLogxK
U2 - 10.1117/12.2579584
DO - 10.1117/12.2579584
M3 - Conference contribution
AN - SCOPUS:85108458318
T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
BT - Integrated Sensors for Biological and Neural Sensing
A2 - Mohseni, Hooman
PB - SPIE
T2 - Integrated Sensors for Biological and Neural Sensing 2021
Y2 - 6 March 2021 through 11 March 2021
ER -