TY - GEN
T1 - Photonic crystal enhanced fluorescence
AU - Cunningham, Brian T.
PY - 2010/5/3
Y1 - 2010/5/3
N2 - Optical resonances produced by photonic crystal surfaces can be designed to substantially amplify the electric field excitation of fluorophores while at the same time increasing the collection efficiency of emitted photons. Because PC surfaces can be produced inexpensively over large areas by replica molding, they offer an effective means for increasing sensitivity for broad classes of surface-based fluorescent assays. In this talk, the design and fabrication of photonic crystal surfaces and detection instrumentation for fluorescent enhancement will be described, along with demonstrated applications in gene expression microarrays and protein biomarker microarrays.
AB - Optical resonances produced by photonic crystal surfaces can be designed to substantially amplify the electric field excitation of fluorophores while at the same time increasing the collection efficiency of emitted photons. Because PC surfaces can be produced inexpensively over large areas by replica molding, they offer an effective means for increasing sensitivity for broad classes of surface-based fluorescent assays. In this talk, the design and fabrication of photonic crystal surfaces and detection instrumentation for fluorescent enhancement will be described, along with demonstrated applications in gene expression microarrays and protein biomarker microarrays.
UR - http://www.scopus.com/inward/record.url?scp=77951548721&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77951548721&partnerID=8YFLogxK
U2 - 10.1117/12.848224
DO - 10.1117/12.848224
M3 - Conference contribution
AN - SCOPUS:77951548721
SN - 9780819479495
T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
BT - Frontiers in Pathogen Detection
T2 - Frontiers in Pathogen Detection: From Nanosensors to Systems
Y2 - 23 January 2010 through 25 January 2010
ER -