Abstract

Optical resonances produced by photonic crystal surfaces can be designed to substantially amplify the electric field excitation of fluorophores while at the same time increasing the collection efficiency of emitted photons. Because PC surfaces can be produced inexpensively over large areas by replica molding, they offer an effective means for increasing sensitivity for broad classes of surface-based fluorescent assays. In this talk, the design and fabrication of photonic crystal surfaces and detection instrumentation for fluorescent enhancement will be described, along with demonstrated applications in gene expression microarrays and protein biomarker microarrays.

Original languageEnglish (US)
Title of host publicationFrontiers in Pathogen Detection
Subtitle of host publicationFrom Nanosensors to Systems
DOIs
StatePublished - May 3 2010
EventFrontiers in Pathogen Detection: From Nanosensors to Systems - San Francisco, CA, United States
Duration: Jan 23 2010Jan 25 2010

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume7553
ISSN (Print)1605-7422

Other

OtherFrontiers in Pathogen Detection: From Nanosensors to Systems
CountryUnited States
CitySan Francisco, CA
Period1/23/101/25/10

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

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