Abstract
Optical resonances produced by photonic crystal surfaces can be designed to substantially amplify the electric field excitation of fluorophores while at the same time increasing the collection efficiency of emitted photons. Because PC surfaces can be produced inexpensively over large areas by replica molding, they offer an effective means for increasing sensitivity for broad classes of surface-based fluorescent assays. In this talk, the design and fabrication of photonic crystal surfaces and detection instrumentation for fluorescent enhancement will be described, along with demonstrated applications in gene expression microarrays and protein biomarker microarrays.
| Original language | English (US) |
|---|---|
| Title of host publication | Frontiers in Pathogen Detection |
| Subtitle of host publication | From Nanosensors to Systems |
| DOIs | |
| State | Published - May 3 2010 |
| Event | Frontiers in Pathogen Detection: From Nanosensors to Systems - San Francisco, CA, United States Duration: Jan 23 2010 → Jan 25 2010 |
Publication series
| Name | Progress in Biomedical Optics and Imaging - Proceedings of SPIE |
|---|---|
| Volume | 7553 |
| ISSN (Print) | 1605-7422 |
Other
| Other | Frontiers in Pathogen Detection: From Nanosensors to Systems |
|---|---|
| Country | United States |
| City | San Francisco, CA |
| Period | 1/23/10 → 1/25/10 |
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Biomaterials
- Atomic and Molecular Physics, and Optics
- Radiology Nuclear Medicine and imaging
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Cite this
Cunningham, B. T. (2010). Photonic crystal enhanced fluorescence. In Frontiers in Pathogen Detection: From Nanosensors to Systems [755302] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 7553). https://doi.org/10.1117/12.848224