Photoacoustic computed tomography correcting for heterogeneity and attenuation

Chao Huang, Liming Nie, Robert W. Schoonover, Lihong V. Wang, Mark A. Anastasio

Research output: Contribution to journalArticlepeer-review

Abstract

We report an investigation of image reconstruction in photoacoustic tomography for objects that possess heterogeneous material and acoustic attenuation distributions. When the object contains materials, such as bone and soft-tissue, that are modeled using power law attenuation models with distinct exponents, we demonstrate that the effects of acoustic attenuation due to the most strongly attenuating material can be compensated for if the attenuation of the other less attenuating material(s) are neglected. Experiments with phantom objects are presented to validated our findings.

Original languageEnglish (US)
Article number061211
JournalJournal of biomedical optics
Volume17
Issue number6
DOIs
StatePublished - Jun 2012
Externally publishedYes

Keywords

  • Attenuation
  • Image reconstruction
  • Photoacoustics
  • Tomography

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Biomedical Engineering

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