Phospholipid modifications in bacteria

Research output: Contribution to journalReview articlepeer-review


Many bacteria alter the acyl chains of their membrane phospholipids in response to changing environmental conditions. Two of these modifications are reviewed: cis→trans isomerization and cyclopropanation of double bonds. The isomerization reaction is now known to be catalyzed by a periplasmic protein that contains a covalently bound heme. Cyclopropanation has been shown to play a role in Mycobacterium tuberculosis pathogenesis and, in Escherichia coli, plays an important role in resistance to acidic conditions.

Original languageEnglish (US)
Pages (from-to)202-205
Number of pages4
JournalCurrent Opinion in Microbiology
Issue number2
StatePublished - 2002

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)
  • Infectious Diseases


Dive into the research topics of 'Phospholipid modifications in bacteria'. Together they form a unique fingerprint.

Cite this