Perspectives on the design and control of multiscale systems

R. D. Braatz, R. C. Alkire, E. Seebauer, E. Rusli, R. Gunawan, T. O. Drews, X. Li, Y. He

Research output: Contribution to journalConference articlepeer-review


New applications in materials, medicine, and computers are being discovered where the control of events at the molecular and nanoscopic scales is critical to product quality, although the primary manipulation of these events during processing occurs at macroscopic length scales. This motivates the creation of tools for the design and control of multiscale systems that have length scales ranging from the atomistic to the macroscopic. This paper describes a systematic approach that consists of stochastic parameter sensitivity analysis, Bayesian parameter estimation applied to ab initio calculations and experimental data, model-based experimental design, hypothesis mechanism selection, and multistep optimization.

Original languageEnglish (US)
Pages (from-to)155-166
Number of pages12
JournalIFAC Proceedings Volumes (IFAC-PapersOnline)
Issue number9
StatePublished - 2004
Event7th IFAC Symposium on Dynamics and Control of Process Systems, DYCOPS 2004 - Cambridge, United States
Duration: Jul 5 2004Jul 7 2004


  • Complex systems
  • Distributed parameter systems
  • Nonlinear systems
  • Optimal control
  • Stochastic systems
  • System sensitivity
  • Uncertain dynamic systems

ASJC Scopus subject areas

  • Control and Systems Engineering


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