Peroxisomal β-oxidation of fatty acids in bovine and rat liver

D. E. Grum, L. R. Hansen, J. K. Drackley

Research output: Contribution to journalArticlepeer-review

Abstract

Hepatic peroxisomal β-oxidation rates were compared in liver homogenates from cows and rats during different nutritional and physiological states. Peroxisomal oxidation in liver homogenates from cows represented 50% and 77% of the total capacity for the initial cycle of β-oxidation of palmitate and octanoate, respectively, but only 26% and 65% for rats. Lactation or food deprivation did not alter rates of hepatic peroxisomal β-oxidation of palmitate or octanoate in cows. Fasting and clofibrate treatment increased rates of total and peroxisomal β-oxidation of palmitate and octanoate in rat liver.

Original languageEnglish (US)
Pages (from-to)281-292
Number of pages12
JournalComparative Biochemistry and Physiology -- Part B: Biochemistry and
Volume109
Issue number2-3
DOIs
StatePublished - 1994

Keywords

  • Bovine
  • Fasting
  • Fatty acids
  • Lactation
  • Liver
  • Octanoate
  • Palmitate
  • Peroxisome
  • Rat
  • β-Oxidation

ASJC Scopus subject areas

  • Biochemistry
  • Physiology
  • Molecular Biology

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