Peptide post-translational modifications affected by the MALDI-TOF measurement process

Sarah A. Sheeley, Wayne P. Kelley, Lingjun Li, Jonathan V Sweedler

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The post-translation chemical modifications (PTM) of neuropeptides were discussed. The study was carried out by using matrix-assisted laser deposition ionization time-of-flight (MALDI-TOF) measurements. MALDI-TOF mass spectra were collected using a Voyager DE-STR mass spectrometer equipped with delayed ion extraction. Using MALDI, the observation of the nitrated form is matrix dependent and found only with sinipinc acid where other common matrices yield little or no modified peak.

Original languageEnglish (US)
Title of host publicationProceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics
Pages365-366
Number of pages2
StatePublished - 2002
EventProceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics - Orlando, FL, United States
Duration: Jun 2 2002Jun 6 2002

Other

OtherProceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics
CountryUnited States
CityOrlando, FL
Period6/2/026/6/02

ASJC Scopus subject areas

  • Spectroscopy

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  • Cite this

    Sheeley, S. A., Kelley, W. P., Li, L., & Sweedler, J. V. (2002). Peptide post-translational modifications affected by the MALDI-TOF measurement process. In Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics (pp. 365-366)