Patient-specific flexible and stretchable devices for cardiac diagnostics and therapy

Sarah R. Gutbrod, Matthew S. Sulkin, John A. Rogers, Igor R. Efimov

Research output: Contribution to journalReview article

Abstract

Advances in material science techniques and pioneering circuit designs have led to the development of electronic membranes that can form intimate contacts with biological tissues. In this review, we present the range of geometries, sensors, and actuators available for custom configurations of electronic membranes in cardiac applications. Additionally, we highlight the desirable mechanics achieved by such devices that allow the circuits and substrates to deform with the beating heart. These devices unlock opportunities to collect continuous data on the electrical, metabolic, and mechanical state of the heart as well as a platform on which to develop high definition therapeutics.

Original languageEnglish (US)
Pages (from-to)244-251
Number of pages8
JournalProgress in Biophysics and Molecular Biology
Volume115
Issue number2-3
DOIs
StatePublished - Aug 1 2014

Fingerprint

Equipment and Supplies
Membranes
Mechanics
Therapeutics

Keywords

  • Bioelectronics
  • Imaging
  • Physiology

ASJC Scopus subject areas

  • Molecular Biology
  • Biophysics

Cite this

Patient-specific flexible and stretchable devices for cardiac diagnostics and therapy. / Gutbrod, Sarah R.; Sulkin, Matthew S.; Rogers, John A.; Efimov, Igor R.

In: Progress in Biophysics and Molecular Biology, Vol. 115, No. 2-3, 01.08.2014, p. 244-251.

Research output: Contribution to journalReview article

Gutbrod, Sarah R. ; Sulkin, Matthew S. ; Rogers, John A. ; Efimov, Igor R. / Patient-specific flexible and stretchable devices for cardiac diagnostics and therapy. In: Progress in Biophysics and Molecular Biology. 2014 ; Vol. 115, No. 2-3. pp. 244-251.
@article{97cbd71c40594b4c9f87101dab7cd203,
title = "Patient-specific flexible and stretchable devices for cardiac diagnostics and therapy",
abstract = "Advances in material science techniques and pioneering circuit designs have led to the development of electronic membranes that can form intimate contacts with biological tissues. In this review, we present the range of geometries, sensors, and actuators available for custom configurations of electronic membranes in cardiac applications. Additionally, we highlight the desirable mechanics achieved by such devices that allow the circuits and substrates to deform with the beating heart. These devices unlock opportunities to collect continuous data on the electrical, metabolic, and mechanical state of the heart as well as a platform on which to develop high definition therapeutics.",
keywords = "Bioelectronics, Imaging, Physiology",
author = "Gutbrod, {Sarah R.} and Sulkin, {Matthew S.} and Rogers, {John A.} and Efimov, {Igor R.}",
year = "2014",
month = "8",
day = "1",
doi = "10.1016/j.pbiomolbio.2014.07.011",
language = "English (US)",
volume = "115",
pages = "244--251",
journal = "Progress in Biophysics and Molecular Biology",
issn = "0079-6107",
publisher = "Elsevier Limited",
number = "2-3",

}

TY - JOUR

T1 - Patient-specific flexible and stretchable devices for cardiac diagnostics and therapy

AU - Gutbrod, Sarah R.

AU - Sulkin, Matthew S.

AU - Rogers, John A.

AU - Efimov, Igor R.

PY - 2014/8/1

Y1 - 2014/8/1

N2 - Advances in material science techniques and pioneering circuit designs have led to the development of electronic membranes that can form intimate contacts with biological tissues. In this review, we present the range of geometries, sensors, and actuators available for custom configurations of electronic membranes in cardiac applications. Additionally, we highlight the desirable mechanics achieved by such devices that allow the circuits and substrates to deform with the beating heart. These devices unlock opportunities to collect continuous data on the electrical, metabolic, and mechanical state of the heart as well as a platform on which to develop high definition therapeutics.

AB - Advances in material science techniques and pioneering circuit designs have led to the development of electronic membranes that can form intimate contacts with biological tissues. In this review, we present the range of geometries, sensors, and actuators available for custom configurations of electronic membranes in cardiac applications. Additionally, we highlight the desirable mechanics achieved by such devices that allow the circuits and substrates to deform with the beating heart. These devices unlock opportunities to collect continuous data on the electrical, metabolic, and mechanical state of the heart as well as a platform on which to develop high definition therapeutics.

KW - Bioelectronics

KW - Imaging

KW - Physiology

UR - http://www.scopus.com/inward/record.url?scp=84908653943&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84908653943&partnerID=8YFLogxK

U2 - 10.1016/j.pbiomolbio.2014.07.011

DO - 10.1016/j.pbiomolbio.2014.07.011

M3 - Review article

C2 - 25106701

AN - SCOPUS:84908653943

VL - 115

SP - 244

EP - 251

JO - Progress in Biophysics and Molecular Biology

JF - Progress in Biophysics and Molecular Biology

SN - 0079-6107

IS - 2-3

ER -