@inproceedings{ae0ee41863fb43648e41c9f20d277ba1,
title = "Patient derived glioblastoma cells activate microglia in a three-dimensional gelatin hydrogel",
abstract = "Statement of Purpose: Glioblastoma (GBM) is the most common and deadly form of brain cancer. Despite the current standard-of-care, patient prognosis is still poor (median survival ~15months; 5+ year survival <10%). Tumor-associated microglia and macrophages (TAMs) in the GBM tumor microenvironment (TME) are believed to be powerful regulators of GBM invasion and therapeutic outcomes. This work focuses on investigating crosstalk between patient-derived GBM biospecimens and TAMs within a gelatin hydrogel platform to uncover the role of GBM-microglial interactions on GBM invasion, microglia activation, and therapeutic resistance.",
author = "Chen, {Jee Wei Emily} and Jan Lumibao and Gaskins, {H Rex} and Harley, {Brendan A}",
note = "Publisher Copyright: {\textcopyright} 2019 Omnipress - All rights reserved.; 42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence ; Conference date: 03-04-2019 Through 06-04-2019",
year = "2019",
language = "English (US)",
series = "Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium",
publisher = "Society for Biomaterials",
pages = "652",
booktitle = "Society for Biomaterials Annual Meeting and Exposition 2019",
}