Paternal care in a fish: Epigenetics and fitness enhancing effects on offspring anxiety

Katie E. McGhee, Alison M. Bell

Research output: Contribution to journalArticlepeer-review

Abstract

In many animals, including humans, interactions with caring parents can have long-lasting effects on offspring sensitivity to stressors. However, whether these parental effects impact offspring fitness in nature is often unclear. In addition, despite evidence that maternal care can influence offspring behaviour via epigenetic alterations to the genome, it remains unclear whether paternal care has similar effects. Here, we show in three-spined sticklebacks, a fish in which fathers are the sole provider of offspring care, that the direct care provided by fathers affects offspring anxiety and the potential for epigenetic alterations to the offspring genome. We find that families are differentially vulnerable to early stress and fathers can compensate for this differential sensitivity with the quality of their care. This variation in paternal care is also linked to the expression in offspring brains of a DNA methyltransferase (Dnmt3a) responsible for de novo methylation. We show that these paternal effects are potentially adaptive and anxious offspring are unlikely to survive an encounter with a predator. By supplying offspring care, fathers reduce offspring anxiety thereby increasing the survival of their offspring— not in the traditional sense through resource provisioning but through an epigenetic effect on offspring behavioural development.

Original languageEnglish (US)
Article number20141146
JournalProceedings of the Royal Society B: Biological Sciences
Volume281
Issue number1794
DOIs
StatePublished - Sep 17 2014

Keywords

  • Behavioural programming
  • Early life stress
  • Methylation
  • Survival
  • Three-spined stickleback
  • Transgenerational plasticity

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)
  • Environmental Science(all)
  • Agricultural and Biological Sciences(all)

Fingerprint Dive into the research topics of 'Paternal care in a fish: Epigenetics and fitness enhancing effects on offspring anxiety'. Together they form a unique fingerprint.

Cite this