Partial cloning and expression pattern analyses of fibroblast growth factor-like cDNA in Xenopus oocytes

Hyun Hee Kim, Chemyong Ko, Hae Moon Chung, Won Sun Kim, Sang Uk Nham

Research output: Contribution to journalArticlepeer-review

Abstract

We cloned a partial sequence of novel Xenopus cDNA which showed a siginficant homology to fibroblast growth factor cDNA. This gene was expressed maternally and presented throughout embryonic stages. The level of this gene expression was gradually decreased during the developmental stages from fertilized egg to early gas-trula and began to increase after mid gastrula stage, indicating zygotical expression of the gene after mid gastrula. The wholemount in situ hybridization analysis revealed that this novel gene was expressed in somites, notochord, central nervous system, eye, gill slit and cement gland. These expression analyses indicated that this novel gene might be invoved in neuronal development or formation of chordamesoderm.

Original languageEnglish (US)
Pages (from-to)257-265
Number of pages9
JournalKorean Journal of Genetics
Volume19
Issue number3
StatePublished - Dec 1 1997
Externally publishedYes

Keywords

  • Expression pattern
  • Fibroblast growth factor (FGF)
  • Xenopus
  • cDNA cloning

ASJC Scopus subject areas

  • Genetics

Fingerprint Dive into the research topics of 'Partial cloning and expression pattern analyses of fibroblast growth factor-like cDNA in Xenopus oocytes'. Together they form a unique fingerprint.

Cite this