Palladium-Catalyzed Silylation of Aryl Bromides Leading to Functionalized Aryldimethylsilanols

Scott E. Denmark, Jeffrey M. Kallemeyn

Research output: Contribution to journalArticlepeer-review


Equation presented. A mild and general palladium-catalyzed insertion of 1,2-diethoxy-1,1,2,2-tetramethyldisilane into a variety of aryl bromides affords the aryldimethylsilyl ethers in high yields. Hydrolysis of the ethers under pH-optimized conditions results in the exclusive formation of the desired aryldimethylsilanols.

Original languageEnglish (US)
Pages (from-to)3483-3486
Number of pages4
JournalOrganic Letters
Issue number19
StatePublished - Sep 18 2003

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry


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