PAC-1 combination therapy

Jessie Peh; Paul J Hergenrother

PAC-1 combination therapy

Jessie Peh (Inventor), Paul J Hergenrother (Inventor)

Research output: Patent

Abstract

Compositions and methods for the induction of cancer cell death. The compositions and methods of using them include use of compositions in therapy for the treatment of cancer and for the selective induction of apoptosis in cancer cells. The drug combinations described herein can be synergistic and can have lower neurotoxicity effects than the same amounts of other compounds and combinations of compounds and can be effective when a particular cancer has become resistant to previously administered therapies.

Original language	English (US)
U.S. patent number	11129830
Filing date	6/10/19
State	Published - Sep 28 2021

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title = "PAC-1 combination therapy",

abstract = "Compositions and methods for the induction of cancer cell death. The compositions and methods of using them include use of compositions in therapy for the treatment of cancer and for the selective induction of apoptosis in cancer cells. The drug combinations described herein can be synergistic and can have lower neurotoxicity effects than the same amounts of other compounds and combinations of compounds and can be effective when a particular cancer has become resistant to previously administered therapies.",

author = "Jessie Peh and Hergenrother, {Paul J}",

note = "GOVERNMENT SUPPORT This invention was made with government support under Grant No. R01 CA120439 awarded by the National Institutes of Health. The government has certain rights in the invention. ; 11129830",

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day = "28",

language = "English (US)",

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T1 - PAC-1 combination therapy

AU - Peh, Jessie

AU - Hergenrother, Paul J

N1 - GOVERNMENT SUPPORT This invention was made with government support under Grant No. R01 CA120439 awarded by the National Institutes of Health. The government has certain rights in the invention.

PY - 2021/9/28

Y1 - 2021/9/28

N2 - Compositions and methods for the induction of cancer cell death. The compositions and methods of using them include use of compositions in therapy for the treatment of cancer and for the selective induction of apoptosis in cancer cells. The drug combinations described herein can be synergistic and can have lower neurotoxicity effects than the same amounts of other compounds and combinations of compounds and can be effective when a particular cancer has become resistant to previously administered therapies.

AB - Compositions and methods for the induction of cancer cell death. The compositions and methods of using them include use of compositions in therapy for the treatment of cancer and for the selective induction of apoptosis in cancer cells. The drug combinations described herein can be synergistic and can have lower neurotoxicity effects than the same amounts of other compounds and combinations of compounds and can be effective when a particular cancer has become resistant to previously administered therapies.

M3 - Patent

M1 - 11129830

Y2 - 2019/06/10

ER -

PAC-1 combination therapy

Abstract

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