@article{e4bf6b0380244358990d603376ae4c85,
title = "P-TEFb: Finding its ways to release promoter-proximally paused RNA polymerase II",
abstract = "The release of a paused Pol II depends on the recruitment of P-TEFb. Recent studies showed that both active P-TEFb and inactive P-TEFb (7SK snRNP) can be recruited to the promoter regions of global genes by different mechanisms. Here, we summarize the recent advances on these distinct recruitment mechanisms.",
keywords = "7SK snRNP, Brd4, KAP1, P-TEFb, RNA Pol II, SEC, promoter-proximal pausing, transcription elongation",
author = "You Li and Min Liu and Chen, {Lin Feng} and Ruichuan Chen",
note = "Funding Information: This work was supported by National Natural Science Foundation of China (81361120386, 31570751, 31270809 and 30930046 to R.C.; 31501096 to M.L.); 973 program (2013CB917802 to R.C.); NIH-CA179511 (to L.F.C.); the Fundamental Research Funds for the Central Universities (20720150053 to M.L.); and the NSFC for Fostering Talents in Basic Research (J1310027 to Y.C). Publisher Copyright: {\textcopyright} 2017 Taylor & Francis.",
year = "2018",
month = mar,
day = "15",
doi = "10.1080/21541264.2017.1281864",
language = "English (US)",
volume = "9",
pages = "88--94",
journal = "Transcription",
issn = "2154-1264",
publisher = "Friedrich-Berlin-Verlag",
number = "2",
}