TY - JOUR
T1 - Oxidation State of Capping Agent Affects Spatial Reactivity on Gold Nanorods
AU - Hinman, Joshua G.
AU - Eller, Jonathan R.
AU - Lin, Wayne
AU - Li, Ji
AU - Li, Junheng
AU - Murphy, Catherine J.
N1 - Publisher Copyright:
© 2017 American Chemical Society.
PY - 2017/7/26
Y1 - 2017/7/26
N2 - Despite enormous progress toward controlling the shapes and surface chemistry of colloidal nanoparticles, spatial control of nanoparticle surface chemistry remains a major challenge. In recent years, there have been tantalizing reports demonstrating anisotropic silica coating of gold nanorods in which silica is deposited only on the sides by functionalizing the nanorods with poly(ethylene glycol) methyl ether thiol (PEG-thiol) prior to silica coating, but such results have been difficult to reproduce. We report that the oxidation state of PEG-thiol is key to anisotropic silica coating, with the disulfide, not the thiol, leading to side silica coating. PEG-disulfide appears to selectively functionalize the ends of gold nanorods, and robust methods are developed to reliably deposit side silica shells on PEG-disulfide functionalized gold nanorods.
AB - Despite enormous progress toward controlling the shapes and surface chemistry of colloidal nanoparticles, spatial control of nanoparticle surface chemistry remains a major challenge. In recent years, there have been tantalizing reports demonstrating anisotropic silica coating of gold nanorods in which silica is deposited only on the sides by functionalizing the nanorods with poly(ethylene glycol) methyl ether thiol (PEG-thiol) prior to silica coating, but such results have been difficult to reproduce. We report that the oxidation state of PEG-thiol is key to anisotropic silica coating, with the disulfide, not the thiol, leading to side silica coating. PEG-disulfide appears to selectively functionalize the ends of gold nanorods, and robust methods are developed to reliably deposit side silica shells on PEG-disulfide functionalized gold nanorods.
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U2 - 10.1021/jacs.7b06391
DO - 10.1021/jacs.7b06391
M3 - Article
C2 - 28696107
AN - SCOPUS:85026294400
SN - 0002-7863
VL - 139
SP - 9851
EP - 9854
JO - Journal of the American Chemical Society
JF - Journal of the American Chemical Society
IS - 29
ER -