Overexpression of SREBF chaperone (SCAP) enhances nuclear SREBP1 translocation to upregulate fatty acid synthase (FASN) gene expression in bovine mammary epithelial cells

Keyphrases

• Overexpression 100%
• Gene Expression 100%
• Chaperone 100%
• SREBF1 100%
• Fatty Acid Synthase Gene 100%
• Sterol Regulatory Element-binding protein-1c (SREBP-1c) 100%
• Bovine Mammary Epithelial Cells 100%
• Fatty Acid Synthase 66%
• Expression Vector 25%
• Co-overexpression 25%
• Nuclear Translocation 16%
• Ruminants 16%
• Non-ruminants 16%
• Lipid Droplet Formation 16%
• Binding Site 8%
• Immunofluorescence 8%
• Quantitative PCR 8%
• Western Blot 8%
• Gene Transcription 8%
• Overexpressing 8%
• Transcriptional Regulation 8%
• Transcription Factor Binding Sites 8%
• Bioinformatics Analysis 8%
• Increased Activity 8%
• MRNA Abundance 8%
• Mammary Gland 8%
• Milk Fat 8%
• Epithelial Cell Line 8%
• MAC-T 8%
• Luciferase Assay 8%
• Protein Abundance 8%
• Lipid Droplets 8%
• PcDNA3.1 8%
• Sterol Response Element 8%

Biochemistry, Genetics and Molecular Biology

• Gene Expression 100%
• Fatty Acid Synthase 100%
• Sterol Regulatory Element Binding Protein 1 100%
• Promoter Region 33%
• Expression Vector 25%
• Lipid Droplet 25%
• Binding Site 16%
• Transfection 8%
• Transcription Factors 8%
• Response Element 8%
• Enzyme 8%
• Genetic Transcription 8%
• Immunofluorescence 8%
• Real-Time Polymerase Chain Reaction 8%
• Maturation 8%
• Luciferase 8%
• Western Blot 8%
• Sterol 8%
• Messenger RNA 8%
• Bioinformatics 8%