Optically guided mass spectrometry to screen microbial colonies for directed enzyme evolution

Keyphrases

• Mass Spectrometry 100%
• Directed Enzyme Evolution 100%
• Enzymatic Reaction 100%
• Microbial Colonies 100%
• High Sensitivity 50%
• High-throughput 50%
• Directed Evolution 50%
• Label-free 50%
• High-throughput Methods 50%
• Matrix-assisted Laser Desorption Ionization-time of Flight Mass Spectrometry (MALDI-TOF MS) 50%
• Large Population 50%
• Antibiotics 50%
• Biochemical Pathways 50%
• Enzyme Engineering 50%
• Acquisition Efficiency 50%
• Multi-enzyme 50%
• Rhamnolipid 50%
• Computational Algorithm 50%
• Peptidic 50%
• High-throughput Phenotyping 50%
• Mass Spectral Data 50%
• Bacterial Colony 50%
• Plantazolicin 50%
• Natural Product Biosynthesis 50%
• Rapid Profiling 50%

Biochemistry, Genetics and Molecular Biology

• Mass Spectrometry 100%
• Enzyme 100%
• Anabolism 50%
• Matrix-Assisted Laser Desorption/Ionization 50%
• Time-of-Flight Mass Spectrometry 50%
• Enzyme Engineering 50%
• Bacterium Colony 50%
• Rhamnolipid 50%

Chemistry

• Mass Spectrometry 100%
• Enzymatic Reaction 100%
• Matrix Assisted Laser Desorption Ionization - Time of Flight (MALDI-TOF) 50%
• Mass Spectrum Parameter 50%
• Natural Product 50%