Optical properties of acute kidney injury measured by quantitative phase imaging

Sungbea Ban, Eunjung Min, Songyee Baek, Hyug Moo Kwon, Gabriel Popescu, Woonggyu Jung

Research output: Contribution to journalArticlepeer-review


The diagnosis of acute kidney disease (AKI) has been examined mainly by histology, immunohistochemistry and western blot. Though these approaches are widely accepted in the field, it has an inherent limitation due to the lack of high-throughput and quantitative information. For a better understanding of prognosis in AKI, we present a new approach using quantitative phase imaging combined with a wide-field scanning platform. Through the phase-delay information from the tissue, we were able to predict a stage of AKI based on various optical properties such as light scattering coefficient and anisotropy. These optical parameters quantify the deterioration process of the AKI model of tissue. Our device would be a very useful tool when it is required to deliver fast feedback of tissue pathology or when diseases are related to mechanical properties such as fibrosis.

Original languageEnglish (US)
Article number#319886
JournalBiomedical Optics Express
Issue number3
StatePublished - Mar 1 2018

ASJC Scopus subject areas

  • Biotechnology
  • Atomic and Molecular Physics, and Optics


Dive into the research topics of 'Optical properties of acute kidney injury measured by quantitative phase imaging'. Together they form a unique fingerprint.

Cite this