Optical manipulation of silicon microparticles in biological environments

Amy L. Oldenburg, Se Jung Moon, Karthy M. Kasi, Taekyung Kim, Chuen Ho, Rolf Timp, Hyungsoo Choi, Vladimir I. Gelfand, Joe Roland, Kyekyoon Kim, Stephen A. Boppart, Gregory L. Timp

Research output: Contribution to journalConference article


Manipulation of micron-scale silicon particles has been investigated with optical tweezers implemented using a two-dimensional scanning trap driven with acousto-optic modulators. Spheres of latex, Poly(methyl methacrylate) (PMMA), silica, and silver-coated PMMA have been utilized to calibrate transverse trapping forces. The goal of this work is to non-invasively manipulate 10-20μm silicon-based devices in and around cells.

Original languageEnglish (US)
Pages (from-to)249-255
Number of pages7
JournalProceedings of SPIE - The International Society for Optical Engineering
StatePublished - Nov 20 2003
EventManipulation and Analysis of Biomolecules, Cells , and Tissues - San Jose, CA, United States
Duration: Jan 28 2003Jan 29 2003



  • Integrated circuits
  • Optical trapping
  • Optical tweezers
  • Silicon

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

Cite this

Oldenburg, A. L., Moon, S. J., Kasi, K. M., Kim, T., Ho, C., Timp, R., Choi, H., Gelfand, V. I., Roland, J., Kim, K., Boppart, S. A., & Timp, G. L. (2003). Optical manipulation of silicon microparticles in biological environments. Proceedings of SPIE - The International Society for Optical Engineering, 4962, 249-255. https://doi.org/10.1117/12.478123