Optical characterization and polarization calibration for rigid endoscopes

Missael Garcia, Viktor Gruev

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Polarization measurements give orthogonal information to spectral images making them a great tool in the characterization of environmental parameters in nature. Thus, polarization imagery has proven to be remarkably useful in a vast range of biomedical applications. One such application is the early diagnosis of flat cancerous lesions in murine colorectal tumor models, where polarization data complements NIR fluorescence analysis. Advances in nanotechnology have led to compact and precise bio-inspired imaging sensors capable of accurately co-registering multidimensional spectral and polarization information. As more applications emerge for these imagers, the optics used in these instruments get very complex and can potentially compromise the original polarization state of the incident light. Here we present a complete optical and polarization characterization of three rigid endoscopes of size 1.9mm x 10cm (Karl Storz, Germany), 5mm x 30cm, and 10mm x 33cm (Olympus, Germany), used in colonoscopy for the prevention of colitis-associated cancer. Characterization results show that the telescope optics act as retarders and effectively depolarize the linear component. These incorrect readings can cause false-positives or false-negatives leading to an improper diagnosis. In this paper, we offer a polarization calibration scheme for these endoscopes based on Mueller calculus. By modeling the optical properties from training data as real-valued Mueller matrices, we are able to successfully reconstruct the initial polarization state acquired by the imaging system.

Original languageEnglish (US)
Title of host publicationEndoscopic Microscopy XII
EditorsGuillermo J. Tearney, Thomas D. Wang
PublisherSPIE
ISBN (Electronic)9781510605213
DOIs
StatePublished - Jan 1 2017
EventEndoscopic Microscopy XII - San Francisco, United States
Duration: Jan 29 2017Jan 30 2017

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume10040
ISSN (Print)1605-7422

Other

OtherEndoscopic Microscopy XII
CountryUnited States
CitySan Francisco
Period1/29/171/30/17

Keywords

  • Calibration
  • Characterization
  • Endoscope
  • Polarization

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

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  • Cite this

    Garcia, M., & Gruev, V. (2017). Optical characterization and polarization calibration for rigid endoscopes. In G. J. Tearney, & T. D. Wang (Eds.), Endoscopic Microscopy XII [1004008] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10040). SPIE. https://doi.org/10.1117/12.2252969