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On the kinetics of polyplex endocytic trafficking: Implications for gene delivery vector design
M. Laird Forrest, Daniel W. Pack
Chemical and Biomolecular Engineering
Carl R. Woese Institute for Genomic Biology
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Keyphrases
Gene Delivery
100%
Poly-L-lysine
100%
Vector Design
100%
Polyplex
100%
Gene Delivery Vector
100%
Endocytic Trafficking
100%
Polyethylenimine
66%
Chloroquine
66%
Endocytic Vesicles
66%
Endocytic Compartment
66%
DNA Complex
33%
Delivery Mechanisms
33%
Flow Cytometry
33%
Acidic Environment
33%
Physical Barrier
33%
Lysosome
33%
New Vectors
33%
Synthetic Gene
33%
Gene Therapy Vectors
33%
Polymer Design
33%
PH Microenvironment
33%
Pharmacology, Toxicology and Pharmaceutical Science
Gene Delivery
100%
Lysine
75%
Polyethyleneimine
50%
Chloroquine
50%
Buffer
25%
Flow Cytometry
25%
Synthetic DNA
25%
Prednicarbate
25%
Neuroscience
Gene Delivery
100%
Lysine
75%
Chloroquine
50%
Synthetic DNA
25%
Flow Cytometry
25%
Internalization
25%
Lysosome
25%
Prednicarbate
25%
Immunology and Microbiology
Gene Targeting
100%
Chloroquine
50%
Endosome
50%
Internalization
25%
Lysosome
25%