Nuclear hormone receptors: Ligand-activated regulators of transcription and diverse cell responses

John A. Katzenellenbogen; Benita S. Katzenellenbogen

doi:10.1016/S1074-5521(96)90143-X

Nuclear hormone receptors: Ligand-activated regulators of transcription and diverse cell responses

Research output: Contribution to journal › Review article › peer-review

Abstract

Signal transduction via nuclear hormone receptors is unusual in that the hormone ligand forms an integral part of the protein complex involved in DNA binding and transcriptional activation. New structural and biochemical results have begun to unravel how these receptors produce different effects in different cells, and the structural changes involved in transcriptional activation.

Original language	English (US)
Pages (from-to)	529-536
Number of pages	8
Journal	Chemistry and Biology
Volume	3
Issue number	7
DOIs	https://doi.org/10.1016/S1074-5521(96)90143-X
State	Published - Jul 1996

ASJC Scopus subject areas

Biochemistry
Molecular Medicine
Molecular Biology
Pharmacology
Drug Discovery
Clinical Biochemistry

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10.1016/S1074-5521(96)90143-X

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title = "Nuclear hormone receptors: Ligand-activated regulators of transcription and diverse cell responses",

abstract = "Signal transduction via nuclear hormone receptors is unusual in that the hormone ligand forms an integral part of the protein complex involved in DNA binding and transcriptional activation. New structural and biochemical results have begun to unravel how these receptors produce different effects in different cells, and the structural changes involved in transcriptional activation.",

author = "Katzenellenbogen, \{John A.\} and Katzenellenbogen, \{Benita S.\}",

note = "We are grateful for support of research performed in our laboratories by grants from the National Institutes of Health. We thank Richard L Wagner for providing Figure 7.",

year = "1996",

month = jul,

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language = "English (US)",

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journal = "Chemistry and Biology",

issn = "1074-5521",

publisher = "Elsevier Limited",

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TY - JOUR

T1 - Nuclear hormone receptors

T2 - Ligand-activated regulators of transcription and diverse cell responses

AU - Katzenellenbogen, John A.

AU - Katzenellenbogen, Benita S.

N1 - We are grateful for support of research performed in our laboratories by grants from the National Institutes of Health. We thank Richard L Wagner for providing Figure 7.

PY - 1996/7

Y1 - 1996/7

N2 - Signal transduction via nuclear hormone receptors is unusual in that the hormone ligand forms an integral part of the protein complex involved in DNA binding and transcriptional activation. New structural and biochemical results have begun to unravel how these receptors produce different effects in different cells, and the structural changes involved in transcriptional activation.

AB - Signal transduction via nuclear hormone receptors is unusual in that the hormone ligand forms an integral part of the protein complex involved in DNA binding and transcriptional activation. New structural and biochemical results have begun to unravel how these receptors produce different effects in different cells, and the structural changes involved in transcriptional activation.

UR - https://www.scopus.com/pages/publications/0030199294

UR - https://www.scopus.com/pages/publications/0030199294#tab=citedBy

U2 - 10.1016/S1074-5521(96)90143-X

DO - 10.1016/S1074-5521(96)90143-X

M3 - Review article

C2 - 8807884

AN - SCOPUS:0030199294

SN - 1074-5521

VL - 3

SP - 529

EP - 536

JO - Chemistry and Biology

JF - Chemistry and Biology

IS - 7

ER -

Nuclear hormone receptors: Ligand-activated regulators of transcription and diverse cell responses

Abstract

ASJC Scopus subject areas

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