Nuclear hormone receptors: Ligand-activated regulators of transcription and diverse cell responses

John A. Katzenellenbogen, Benita S. Katzenellenbogen

Research output: Contribution to journalReview article

Abstract

Signal transduction via nuclear hormone receptors is unusual in that the hormone ligand forms an integral part of the protein complex involved in DNA binding and transcriptional activation. New structural and biochemical results have begun to unravel how these receptors produce different effects in different cells, and the structural changes involved in transcriptional activation.

Original languageEnglish (US)
Pages (from-to)529-536
Number of pages8
JournalChemistry and Biology
Volume3
Issue number7
DOIs
StatePublished - Jul 1996

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmacology
  • Drug Discovery
  • Clinical Biochemistry

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