Novel centrality metrics for studying essentiality in protein-protein interaction networks based on group structures

Keyphrases

• Group Structure 100%
• Network Applications 100%
• Protein-protein Interaction Network 100%
• Centrality Measures 100%
• Computational Complexity 33%
• Metric Basis 33%
• Representative Structures 33%
• Problem Complexity 33%
• Solution Approach 33%
• Helicobacter Pylori (H. pylori) 33%
• Specific Structure 33%
• Specific Pattern 33%
• Single Node 33%
• Commercial Solver 33%
• Mixed Integer Programming Formulations 33%
• Combinatorial Branch-and-bound 33%
• Bound Solution 33%
• Identifying Essential Proteins 33%

Computer Science

• Centrality Metric 100%
• Group Structure 100%
• Computational Complexity 33%
• Branch-and-Bound Algorithm Design 33%
• Problem Complexity 33%
• Mixed Integer Programming 33%