Nosema ceranae and nosema disease in honey bee.

Wei-Fone Huang, Leellen Solter, Chung-Hsiung Wang

Research output: Chapter in Book/Report/Conference proceedingConference contribution


Nosema ceranae is one of two pathogens causing “nosema disease” in honey bees. This microsporidium, relatively recently described, and N. apis, known for over 100 years, share characteristics such as sensitivity to fumagillin and similar morphology under light microscopy. Genetic approaches and/or TEM observations are necessary to distinguish these related species. N. ceranae is reported to have spread to Apis species worldwide and replaced N. apis in some areas, even before it was recognized and described in the Asian honey bee in 1996. There remain questions about N. ceranae transmission and its replacement of N. apis. Symptoms resulting from N. ceranae infection that we found were similar to those of N. apis, including swollen midgut tissues and crawling behavior, but the bees developed these typical symptoms in only a few sites. The nature of symptoms may be affected by environmental factors or differences among intra-specific strains of N. ceranae. We attempted to identify intra-species strains using rDNA and intergenic spacers of the rDNA repeat unit, common molecular markers used for microsporidia. The rDNA and spacer sequences were too conserved to distinguish the strains; however, by comparing rDNA sequences, we found another yettobe- identified Nosema species.
Original languageEnglish (US)
Title of host publication42nd Annual Meeting of the Society for Invertebrate Pathology August 16-20, 2009, Park City, Utah
StatePublished - 2009


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