Nonhematopoietic peroxisome proliferator-activated receptor-α protects against cardiac injury and enhances survival in experimental polymicrobial sepsis

Keyphrases

• Peroxisome Proliferator-activated Receptor 100%
• Nonhematopoietic 100%
• Cardiac Injury 100%
• Polymicrobial Sepsis 100%
• Null Mice 40%
• Wild Mice 25%
• Sepsis 25%
• Cecal Puncture 15%
• Cecal Ligation 15%
• Receptor Expression 10%
• Marrow 10%
• End-organ Disease 10%
• Transcription Factor 5%
• Receptor-mediated 5%
• Bone Marrow 5%
• Energy Production 5%
• Histologic 5%
• Fatty Acids 5%
• Clinical Outcomes 5%
• Euthanized 5%
• Tissue Analysis 5%
• Cellular Metabolism 5%
• Laboratory Investigation 5%
• Prospective Randomized Trial 5%
• Fatty Acid Oxidation 5%
• Survival Benefit 5%
• Troponin Levels 5%
• Reduced Survival 5%
• Plasma Analysis 5%
• Circulating Leukocytes 5%
• Injury Severity Score 5%
• Receptor Status 5%
• Elevated Troponin 5%
• Bone Marrow chimeric Mice 5%

Pharmacology, Toxicology and Pharmaceutical Science

• Peroxisome Proliferator Activated Receptor 100%
• Sepsis 100%
• Heart Injury 100%
• Knockout Mouse 42%
• Wild Type Mouse 26%
• Fatty Acid 10%
• Preclinical Study 5%
• Transcription Factors 5%
• Troponin 5%
• Organ Injury 5%

Immunology and Microbiology

• Cardiac Troponin 5%