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Non-modular fatty acid synthases yield distinct N-terminal acylation in ribosomal peptides
Hengqian Ren
, Chunshuai Huang
, Yuwei Pan
, Shravan R. Dommaraju
, Haiyang Cui
, Maolin Li
, Mayuresh G. Gadgil
, Douglas A. Mitchell
,
Huimin Zhao
Chemistry
Carl R. Woese Institute for Genomic Biology
Chemical and Biomolecular Engineering
Bioengineering
Biomedical and Translational Sciences
Research output
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Contribution to journal
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Article
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peer-review
Overview
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Keyphrases
Acylation
100%
Fatty Acid Synthase
100%
RiPPs
100%
Ribosomal Peptide
100%
Fatty Acids
33%
Lipopeptide
33%
Post-translational Modification
16%
Condensation
16%
Bioengineering
16%
Natural Products
16%
N-terminus
16%
Substructure
16%
Product Family
16%
Modified Peptide
16%
Fatty Acid Pathway
16%
Coenzyme A
16%
Membrane Targeting
16%
Fatty Acyls
16%
Acyl Carrier Protein
16%
Acyltransferase
16%
4-hydroxy-2
16%
Methylmalonyl-CoA
16%
Genome Mining
16%
Hybrid Molecules
16%
Ribosomally Synthesized
16%
Promiscuous Activity
16%
Tailoring Reactions
16%
Biochemistry, Genetics and Molecular Biology
N-Terminus
100%
Fatty Acid Synthase
100%
Acylation
100%
Lipopeptide
100%
Anabolism
50%
Posttranslational Modification
50%
Enzyme
50%
Synthase
50%
N-Acetyltransferase
50%
Acyl Carrier Protein
50%
Coenzyme A
50%
Methylmalonyl-CoA
50%