Abstract
Conventional methods of measuring heating in vivo are invasive and therefore interfere with heat propagation. Developed is a sensitive non-invasive method for temperature measurement using in vivo magnetic resonance spectroscopy (MRS) of the temperature dependent chemical shift of the cobalt (III) nucleus. Tris(ethylenediamine) cobalt (III) trichloride was encapsulated in liposomes and injected into seven rats. After 5 minutes of CW ultrasound exposure, the chemical shift of the cobalt complex indicated that the temperature rise within the liver was 2.0 ± 1.2 °C. Results indicate that experimental values agree with the heating theory.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1829-1831 |
| Number of pages | 3 |
| Journal | Proceedings of the IEEE Ultrasonics Symposium |
| Volume | 3 |
| State | Published - 1994 |
| Event | Proceedings of the 1994 IEEE Ultrasonics Symposium. Part 1 (of 3) - Cannes, Fr Duration: Nov 1 1994 → Nov 4 1994 |
ASJC Scopus subject areas
- Acoustics and Ultrasonics