Non-antibiotic feed additives in diets for pigs: A review

Yanhong Liu, Charmaine D. Espinosa, Jerubella J. Abelilla, Gloria A. Casas, L. Vanessa Lagos, Su A. Lee, Woong B. Kwon, John K. Mathai, Diego M.D.L. Navarro, Neil W. Jaworski, Hans H. Stein

Research output: Contribution to journalReview articlepeer-review


A number of feed additives are marketed to assist in boosting the pigs’ immune system, regulate gut microbiota, and reduce negative impacts of weaning and other environmental challenges. The most commonly used feed additives include acidifiers, zinc and copper, prebiotics, direct-fed microbials, yeast products, nucleotides, and plant extracts. Inclusion of pharmacological levels of zinc and copper, certain acidifiers, and several plant extracts have been reported to result in improved pig performance or improved immune function of pigs. It is also possible that use of prebiotics, direct-fed microbials, yeast, and nucleotides may have positive impacts on pig performance, but results have been less consistent and there is a need for more research in this area.

Original languageEnglish (US)
Pages (from-to)113-125
Number of pages13
JournalAnimal Nutrition
Issue number2
StatePublished - Jun 2018


  • Acidifiers
  • Direct-fed microbials
  • Minerals
  • Pigs
  • Plant extracts
  • Prebiotics

ASJC Scopus subject areas

  • Food Animals
  • Animal Science and Zoology


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