New vistas in organoelement chemistry

Scott E. Denmark, Beritte L. Christenson, Stephen P. O'Connor, Noriaki Murase

Research output: Contribution to journalArticlepeer-review


A selective and efficient protocol for the catalytic asymmetric cyclopropanation of allylic alcohols has been developed. The reaction involves preformation of the ethylzinc alkoxide of the alcohol and reaction with the Furukawa/Simmons-Smith reagent. Zinc iodide has been shown to have a beneficial effect on the rate and enantioselectivity of the reaction. The structural variability in the allylic alcohol as been examined and the reaction was found to proceed smoothly with both E and Z- allylic alcohols with one or two β-substituents, but α-substitution was not well tolerated.

Original languageEnglish (US)
Pages (from-to)23-27
Number of pages5
JournalPure and Applied Chemistry
Issue number1
StatePublished - Jan 1996

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)


Dive into the research topics of 'New vistas in organoelement chemistry'. Together they form a unique fingerprint.

Cite this