Abstract

Characterizing the physical properties of single cells is of great interest for unraveling the heterogeneity in a cell population. Recent advances in micro-systems technologies and quantitative imaging have enabled measurements of the mass and growth of single cells. So far, three classes of techniques have been reported for such measurements. These are suspended micro-channel resonators (SMR) sensors, quantitative phase imaging (QPI), and pedestal resonant sensors. Here we compare the unique merits of each method and discuss their potential to evolve into multi-modal platforms for answering fundamental questions in biology and medicine.

Original languageEnglish (US)
Pages (from-to)646-652
Number of pages7
JournalLab on a chip
Volume14
Issue number4
DOIs
StatePublished - Feb 21 2014

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Cells
Technology
Imaging techniques
Sensors
Medicine
Resonators
Physical properties
Growth
Population

ASJC Scopus subject areas

  • Bioengineering
  • Biochemistry
  • Chemistry(all)
  • Biomedical Engineering

Cite this

New technologies for measuring single cell mass. / Popescu, Gabriel; Park, Kidong; Mir, Mustafa; Bashir, Rashid.

In: Lab on a chip, Vol. 14, No. 4, 21.02.2014, p. 646-652.

Research output: Contribution to journalReview article

Popescu, Gabriel ; Park, Kidong ; Mir, Mustafa ; Bashir, Rashid. / New technologies for measuring single cell mass. In: Lab on a chip. 2014 ; Vol. 14, No. 4. pp. 646-652.
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