New Onto-Tools: Promoter-Express, nsSNPCounter and Onto-Translate

Purvesh Khatri, Valmik Desai, Adi L. Tarca, Sivakumar Sellamuthu, Derek E. Wildman, Roberto Romero, Sorin Draghici

Research output: Contribution to journalArticlepeer-review

Abstract

The Onto-Tools suite is composed of an annotation database and eight complementary, web-accessible data mining tools: Onto-Express, Onto-Compare, Onto-Design, Onto-Translate, Onto-Miner, Pathway-Express, Promoter-Express and nsSNPCounter. Promoter-Express is a new tool added to the Onto-Tools ensemble that facilitates the identification of transcription factor binding sites active in specific conditions. nsSNPCounter is another new tool that allows computation and analysis of synonymous and non-synonymous codon substitutions for studying evolutionary rates of protein coding genes. Onto-Translate has also been enhanced to expand its scope and accuracy by fully utilizing the capabilities of the Onto-Tools database. Currently, Onto-Translate allows arbitrary mappings between 28 types of IDs for 53 organisms. Onto-Tools are freely available at http://vortex.cs.wayne.edu/ Projects.html.

Original languageEnglish (US)
Pages (from-to)W626-W631
JournalNucleic acids research
Volume34
Issue numberWEB. SERV. ISS.
DOIs
StatePublished - Jul 2006

ASJC Scopus subject areas

  • Genetics

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