Neutron scattering in the biological sciences: progress and prospects

Rana Ashkar, Hassina Z. Bilheux, Heliosa Bordallo, Robert Briber, David J.E. Callaway, Xiaolin Cheng, Xiang Qiang Chu, Joseph E. Curtis, Mark Dadmun, Paul Fenimore, David Fushman, Frank Gabel, Kushol Gupta, Frederick Herberle, Frank Heinrich, Liang Hong, John Katsaras, Zvi Kelman, Eugenia Kharlampieva, Gerald R. KnellerAndrey Kovalevsky, Susan Krueger, Paul Langan, Raquel Lieberman, Yun Liu, Mathias Losche, Edward Lyman, Yimin Mao, John Marino, Carla Mattos, Flora Meilleur, Peter Moody, Jonathan D. Nickels, William B. O'Dell, Hugh O'Neill, Ursula Perez-Salas, Judith Peters, Loukas Petridis, Alexei P. Sokolov, Christopher Stanley, Norman Wagner, Michael Weinrich, Kevin Weiss, Troy Wymore, Yang Zhang, Jeremy C. Smith

Research output: Contribution to journalReview articlepeer-review


The scattering of neutrons can be used to provide information on the structure and dynamics of biological systems on multiple length and time scales. Pursuant to a National Science Foundation-funded workshop in February 2018, recent developments in this field are reviewed here, as well as future prospects that can be expected given recent advances in sources, instrumentation and computational power and methods. Crystallography, solution scattering, dynamics, membranes, labeling and imaging are examined. For the extraction of maximum information, the incorporation of judicious specific deuterium labeling, the integration of several types of experiment, and interpretation using high-performance computer simulation models are often found to be particularly powerful.

Original languageEnglish (US)
Pages (from-to)1129-1168
Number of pages40
JournalActa Crystallographica Section D: Structural Biology
Issue number12
StatePublished - Dec 2018


  • biological systems
  • neutron scattering
  • structure and dynamics

ASJC Scopus subject areas

  • Structural Biology


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