Neuromechanical Simulation of Hand Pronation and Supination Task in Parkinson's disease

Liran Ziegelmanl, Yang Hu, Manuel E. Hernandez

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Parkinson's disease is a prevalent and debilitating neurological disorder, where the severity of motor symptoms are frequently monitored using clinical tests that include a hand pronation and supination task. Objective quantification of motor symptoms in persons with Parkinson's disease and detection of dopamine-induced dyskinesias during treatment is important for the management of the most common symptoms in persons with Parkinson's disease. Thus, the development of a neuromechanical model of rhythmic hand pronation and supination may further our understanding of the mechanisms underlying motor symptoms during rhythmic upper extremity tasks in persons with Parkinson's disease. The aim of this study was to create a model for a rhythmic hand pronation and supination task. This was done to create a simulation of a popular diagnostic task used in determining the severity of motor impairments in persons with Parkinson's disease. It is imperative to understand the neural dynamics as well as the physiological constraints placed on a system such as this in both the creation of a usable model as well as understanding the neuromechanical interactions occurring during this diagnostic task. This model of either normal or slowed, clinical behavior, can then serve as a springboard for the creation of models that characterize disordered motor movement and perhaps even the creation of models that could be incorporated into the diagnostic process.

Original languageEnglish (US)
Title of host publication40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages2060-2063
Number of pages4
ISBN (Electronic)9781538636466
DOIs
StatePublished - Oct 26 2018
Event40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018 - Honolulu, United States
Duration: Jul 18 2018Jul 21 2018

Publication series

NameProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
Volume2018-July
ISSN (Print)1557-170X

Other

Other40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018
CountryUnited States
CityHonolulu
Period7/18/187/21/18

Fingerprint

Pronation
Supination
Parkinson Disease
Hand
Dyskinesias
Nervous System Diseases
Upper Extremity
Dopamine

ASJC Scopus subject areas

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

Cite this

Ziegelmanl, L., Hu, Y., & Hernandez, M. E. (2018). Neuromechanical Simulation of Hand Pronation and Supination Task in Parkinson's disease. In 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018 (pp. 2060-2063). [8512605] (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS; Vol. 2018-July). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/EMBC.2018.8512605

Neuromechanical Simulation of Hand Pronation and Supination Task in Parkinson's disease. / Ziegelmanl, Liran; Hu, Yang; Hernandez, Manuel E.

40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018. Institute of Electrical and Electronics Engineers Inc., 2018. p. 2060-2063 8512605 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS; Vol. 2018-July).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Ziegelmanl, L, Hu, Y & Hernandez, ME 2018, Neuromechanical Simulation of Hand Pronation and Supination Task in Parkinson's disease. in 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018., 8512605, Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, vol. 2018-July, Institute of Electrical and Electronics Engineers Inc., pp. 2060-2063, 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018, Honolulu, United States, 7/18/18. https://doi.org/10.1109/EMBC.2018.8512605
Ziegelmanl L, Hu Y, Hernandez ME. Neuromechanical Simulation of Hand Pronation and Supination Task in Parkinson's disease. In 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018. Institute of Electrical and Electronics Engineers Inc. 2018. p. 2060-2063. 8512605. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). https://doi.org/10.1109/EMBC.2018.8512605
Ziegelmanl, Liran ; Hu, Yang ; Hernandez, Manuel E. / Neuromechanical Simulation of Hand Pronation and Supination Task in Parkinson's disease. 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018. Institute of Electrical and Electronics Engineers Inc., 2018. pp. 2060-2063 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).
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