The effect of neurotransmitters on the firing pattern of the postsynaptic cells with which the new neuronal type forms a synapse was investigated. Two sensors capable of detecting the different neurotransmitters which is an electrochemical sensor for neurotransmitter A and a cannula interfaced with capillary electrophoresis for detection of neurotransmitter B was developed. To determine the biological function of the neurotransmitter the electrical output of the circuit as a response to an input stimulus was measured. The detection limit of neurotransmitter A was limited to 40 nmol L-1 and the detection limit of the neurotransmitter B was 80 nmol L-1. the closest position of the dual sensor was approximately 5 μm from the synapse.

Original languageEnglish (US)
Pages (from-to)3-4
Number of pages2
JournalAnalytical and bioanalytical chemistry
Issue number1
StatePublished - Jan 2007

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry


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