TY - JOUR
T1 - Neural sensitivity to eudaimonic and hedonic rewards differentially predict adolescent depressive symptoms over time
AU - Telzer, Eva H.
AU - Fuligni, Andrew J.
AU - Lieberman, Matthew D.
AU - Galván, Adriana
PY - 2014/5/6
Y1 - 2014/5/6
N2 - The pursuit of happiness and reward is an impetus for everyday human behavior and the basis of well-being. Although optimal well-being may be achieved through eudaimonic activities (e.g., meaning and purpose), individuals tend to orient toward hedonic activities (e.g., pleasure seeking), potentially placing them at risk for ill-being. We implemented a longitudinal study and followed adolescents over 1 y to examine whether neural sensitivity to eudaimonic (e.g., prosocial decisions) and hedonic (e.g., selfish rewards and risky decisions) rewards differentially predicts longitudinal changes in depressive symptoms. Ventral striatum activation during eudaimonic decisions predicted longitudinal declines in depressive symptoms, whereas ventral striatum activation to hedonic decisions related to longitudinal increases in depressive symptoms. These findings underscore how the motivational context underlying neural sensitivity to rewards can differentially predict changes in well-being over time. Importantly, to our knowledge, this is the first study to show that striatal activation within an individual can be both a source of risk and protection.
AB - The pursuit of happiness and reward is an impetus for everyday human behavior and the basis of well-being. Although optimal well-being may be achieved through eudaimonic activities (e.g., meaning and purpose), individuals tend to orient toward hedonic activities (e.g., pleasure seeking), potentially placing them at risk for ill-being. We implemented a longitudinal study and followed adolescents over 1 y to examine whether neural sensitivity to eudaimonic (e.g., prosocial decisions) and hedonic (e.g., selfish rewards and risky decisions) rewards differentially predicts longitudinal changes in depressive symptoms. Ventral striatum activation during eudaimonic decisions predicted longitudinal declines in depressive symptoms, whereas ventral striatum activation to hedonic decisions related to longitudinal increases in depressive symptoms. These findings underscore how the motivational context underlying neural sensitivity to rewards can differentially predict changes in well-being over time. Importantly, to our knowledge, this is the first study to show that striatal activation within an individual can be both a source of risk and protection.
KW - Adolescence
KW - Depression
KW - FMRI
UR - http://www.scopus.com/inward/record.url?scp=84899793362&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84899793362&partnerID=8YFLogxK
U2 - 10.1073/pnas.1323014111
DO - 10.1073/pnas.1323014111
M3 - Article
C2 - 24753574
AN - SCOPUS:84899793362
SN - 0027-8424
VL - 111
SP - 6600
EP - 6605
JO - Proceedings of the National Academy of Sciences of the United States of America
JF - Proceedings of the National Academy of Sciences of the United States of America
IS - 18
ER -