Neo-clerodane diterpenes from Ajuga turkestanica

Mary H. Grace, Diana M. Cheng, Ilya Raskin, Mary Ann Lila

Research output: Contribution to journalArticlepeer-review


The ethyl acetate extract of the aerial parts of Ajuga turkestanica afforded 6 neo-clerodane diterpenes, including two novel compounds, 14,15-dihydroajugachin B (1) and 14-hydro-15-methoxyajugachin B (2), in addition to the known diterpenoids chamaepitin (3), ajugachin B (4), ajugapitin (5) and lupulin A (6). Structures were established through exhaustive NMR spectroscopic analysis and chemical transformation in the case of 1. The full 1H and 13C NMR assignment of the C-15 R and S configurations of 14-hydro-15-methoxyajugachin B and chamaepitin were elucidated.

Original languageEnglish (US)
Pages (from-to)81-84
Number of pages4
JournalPhytochemistry Letters
Issue number2
StatePublished - Aug 21 2008


  • 14,15-Dihydroajugachin B
  • 14-Hydro-15-methoxyajugachin B
  • Ajuga turkestanica
  • Labiatae
  • Neo-clerodane diterpenes

ASJC Scopus subject areas

  • Biotechnology
  • Biochemistry
  • Agronomy and Crop Science
  • Plant Science


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