Abstract
Recent developmental brain imaging studies have demonstrated that negatively coupled prefrontal-limbic circuitry implicates the maturation of brain development in adolescents. Using resting-state functional magnetic resonance imaging (rs-fMRI) and independent component analysis (ICA), the present study examined functional network coupling between prefrontal and limbic systems and links to self-control and substance use onset in adolescents. Results suggest that negative network coupling (anti-correlated temporal dynamics) between the right fronto-parietal and limbic resting state networks is associated with greater self-control and later substance use onset in adolescents. These findings increase our understanding of the developmental importance of prefrontal-limbic circuitry for adolescent substance use at the resting-state network level.
Original language | English (US) |
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Pages (from-to) | 35-42 |
Number of pages | 8 |
Journal | Developmental Cognitive Neuroscience |
Volume | 20 |
DOIs | |
State | Published - Aug 1 2016 |
Keywords
- Adolescence
- Fronto-parietal network (FPN)
- Independent component analysis (ICA)
- Intrinsic network connectivity
- Limbic network
- Resting-state fMRI
- Risk-taking behavior
ASJC Scopus subject areas
- Cognitive Neuroscience