Nanoplasmonic resonance energy transfer spectroscopic pH imaging

G. Logan Liu

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Nano plasmonic resonance energy transfer (PRET) spectroscopy is a new sensing technique to study the electronic energy transfer between plasmonic nanoparticles and adsorbed biological/chemical molecules. PRET spectroscopy has been used to detect complex biomolecular activities including conformational change, electron transfer and protein interactions with ultrahigh sensitivity and specificity. Here we demonstrate in vitro and intracellular imaging of pH values using PRET spectroscopy. Potentially submicron spatial resolution and decimal pH sensitivity can be achieved in PRET pH imaging.

Original languageEnglish (US)
Title of host publicationPlasmonics
Subtitle of host publicationNanoimaging, Nanofabrication, and their Applications V
DOIs
StatePublished - 2009
Externally publishedYes
EventPlasmonics: Nanoimaging, Nanofabrication, and their Applications V - San Diego, CA, United States
Duration: Aug 2 2009Aug 6 2009

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume7395
ISSN (Print)0277-786X

Other

OtherPlasmonics: Nanoimaging, Nanofabrication, and their Applications V
Country/TerritoryUnited States
CitySan Diego, CA
Period8/2/098/6/09

Keywords

  • Molecular imaging
  • Plasmonics
  • Resonance energy transfer
  • Spectroscopy

ASJC Scopus subject areas

  • Applied Mathematics
  • Computer Science Applications
  • Electrical and Electronic Engineering
  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics

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