Nanoparticles for imaging, sensing, and therapeutic intervention

Lara K. Bogart, Genevieve Pourroy, Catherine J. Murphy, Victor Puntes, Teresa Pellegrino, Daniel Rosenblum, Dan Peer, Raphaël Lévy

Research output: Contribution to journalArticle

Abstract

Nanoparticles have the potential to contribute to new modalities in molecular imaging and sensing as well as in therapeutic interventions. In this Nano Focus article, we identify some of the current challenges and knowledge gaps that need to be confronted to accelerate the developments of various applications. Using specific examples, we journey from the characterization of these complex hybrid nanomaterials; continue with surface design and (bio)physicochemical properties, their fate in biological media and cells, and their potential for cancer treatment; and finally reflect on the role of animal models to predict their behavior in humans.

Original languageEnglish (US)
Pages (from-to)3107-3122
Number of pages16
JournalACS Nano
Volume8
Issue number4
DOIs
StatePublished - Apr 22 2014

ASJC Scopus subject areas

  • Materials Science(all)
  • Engineering(all)
  • Physics and Astronomy(all)

Fingerprint Dive into the research topics of 'Nanoparticles for imaging, sensing, and therapeutic intervention'. Together they form a unique fingerprint.

  • Cite this

    Bogart, L. K., Pourroy, G., Murphy, C. J., Puntes, V., Pellegrino, T., Rosenblum, D., Peer, D., & Lévy, R. (2014). Nanoparticles for imaging, sensing, and therapeutic intervention. ACS Nano, 8(4), 3107-3122. https://doi.org/10.1021/nn500962q