Nanoneedle: A multifunctional tool for biological studies in living cells

Kyungsuk Yum, Ning Wang, Min Feng Yu

Research output: Contribution to journalArticlepeer-review


Studying biology in living cells is methodologically challenging but highly beneficial. Recent advances in nanobiotechnology offer exciting new opportunities to address this challenge. The nanoneedle technology, as an emerging technology that uses a cell membrane-penetrating nanoneedle to probe and manipulate biological processes in living cells, is expected to play an important role in this endeavor. Here we review the recent development and future direction of the nanoneedle technology for biological studies in living cells. The nanoneedle technology is shown to be powerful and versatile, and can offer numerous new ways to explore biological processes and biophysical properties of living cells with high spatial and temporal precision potentially reaching molecular resolution.

Original languageEnglish (US)
Pages (from-to)363-372
Number of pages10
Issue number3
StatePublished - Mar 19 2010

ASJC Scopus subject areas

  • Materials Science(all)


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