Abstract

Various brain diseases including Alzheimer's disease, stroke, and cancer are major causes of death worldwide. Due to the notion that early diagnosis significantly increases success in treatments, several non-invasive bioimaging modalities such as MRI, CT, and PET are increasingly used to locate pathologic sites in the brain. To further enhance the quality of diagnostic imaging, efforts are incrementally made to couple imaging contrasts of interests to macromolecules or nanoparticles designed to cross over the brain-blood barrier and to bind to pathologic tissue. This chapter will therefore review such important emerging technologies for diagnostic imaging of brain and some preclinical and clinical success, so we can ultimately assist efforts to take diagnosis quality to the next level.

Original languageEnglish (US)
Title of host publicationBiomedical Engineering
Subtitle of host publicationFrontier Research and Converging Technologies
PublisherSpringer International Publishing
Pages77-89
Number of pages13
Volume9
ISBN (Electronic)9783319218137
ISBN (Print)9783319218120
DOIs
StatePublished - Jul 23 2015

Fingerprint

Nanostructures
Diagnostic Imaging
Nanostructured materials
Brain
Imaging techniques
Brain Diseases
Blood-Brain Barrier
Nanoparticles
Early Diagnosis
Cause of Death
Alzheimer Disease
Stroke
Technology
Macromolecules
Magnetic resonance imaging
Tissue
Neoplasms
Positron Emission Tomography Computed Tomography

Keywords

  • Bioimaging
  • Brain
  • Brain-blood barrier
  • Microfabrication
  • Nanoparticle

ASJC Scopus subject areas

  • Engineering(all)
  • Medicine(all)
  • Neuroscience(all)
  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Qin, E., & Kong, H. (2015). Nanomaterials for diagnostic imaging of the brain. In Biomedical Engineering: Frontier Research and Converging Technologies (Vol. 9, pp. 77-89). Springer International Publishing. https://doi.org/10.1007/978-3-319-21813-7_4

Nanomaterials for diagnostic imaging of the brain. / Qin, Ellen; Kong, Hyunjoon.

Biomedical Engineering: Frontier Research and Converging Technologies. Vol. 9 Springer International Publishing, 2015. p. 77-89.

Research output: Chapter in Book/Report/Conference proceedingChapter

Qin, E & Kong, H 2015, Nanomaterials for diagnostic imaging of the brain. in Biomedical Engineering: Frontier Research and Converging Technologies. vol. 9, Springer International Publishing, pp. 77-89. https://doi.org/10.1007/978-3-319-21813-7_4
Qin E, Kong H. Nanomaterials for diagnostic imaging of the brain. In Biomedical Engineering: Frontier Research and Converging Technologies. Vol. 9. Springer International Publishing. 2015. p. 77-89 https://doi.org/10.1007/978-3-319-21813-7_4
Qin, Ellen ; Kong, Hyunjoon. / Nanomaterials for diagnostic imaging of the brain. Biomedical Engineering: Frontier Research and Converging Technologies. Vol. 9 Springer International Publishing, 2015. pp. 77-89
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