NanoEHS - Defining fundamental science needs: No easy feat when the simple itself is complex

Vicki H. Grassian, Amanda J. Haes, Imali A. Mudunkotuwa, Philip Demokritou, Agnes B. Kane, Catherine J. Murphy, James E. Hutchison, Jacqueline A. Isaacs, Young Shin Jun, Barbara Karn, Saiful I. Khondaker, Sarah C. Larsen, Boris L.T. Lau, John M. Pettibone, Omowunmi A. Sadik, Navid B. Saleh, Clayton Teague

Research output: Contribution to journalReview article

Abstract

Nanotechnology is no longer in its infancy and has made significant advances since the implementation of the National Nanotechnology Initiative (NNI) in 2000. Incorporation of nanotechnology in many fields including information technology, medicine, materials, energy, catalysis and cosmetics has led to an increase in engineered nanomaterial (ENM) production, and consequently, increased nanomaterial use. In comparison, the generation of concrete and consistent evidence related to the environmental health and safety of nanomaterials (NanoEHS) is lacking. The main factors contributing to the slower progress in NanoEHS versus conventional EHS are related to the complexity, property transformations, life cycles and behavior of nanomaterials even in carefully controlled environments. Therefore, new systematic, integrated research approaches in NanoEHS are needed for overcoming this complexity and bridging current knowledge gaps. A workshop on "NanoEHS: Fundamental Science Needs" brought together scientists and engineers to identify current fundamental science challenges and opportunities within NanoEHS. Detailed discussions were conducted on identifying the fundamental properties that are critical in NanoEHS, differentiating between conventional and NanoEHS studies as well as understanding, the effect of dynamic transformations on nanometrology, role of dosimetry and mechanistic data gaps in nanotoxicology. An important realization that even simple nanoscale materials can be complex when considering NanoEHS implications was noted several times during the workshop. Despite this fact, a number of fundamental research areas to further the scientific foundation to address NanoEHS needs are suggested.

Original languageEnglish (US)
Pages (from-to)15-27
Number of pages13
JournalEnvironmental Science: Nano
Volume3
Issue number1
DOIs
StatePublished - Feb 1 2016

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ASJC Scopus subject areas

  • Materials Science (miscellaneous)
  • Environmental Science(all)

Cite this

Grassian, V. H., Haes, A. J., Mudunkotuwa, I. A., Demokritou, P., Kane, A. B., Murphy, C. J., Hutchison, J. E., Isaacs, J. A., Jun, Y. S., Karn, B., Khondaker, S. I., Larsen, S. C., Lau, B. L. T., Pettibone, J. M., Sadik, O. A., Saleh, N. B., & Teague, C. (2016). NanoEHS - Defining fundamental science needs: No easy feat when the simple itself is complex. Environmental Science: Nano, 3(1), 15-27. https://doi.org/10.1039/c5en00112a